Description

The laboratory of Dr. Ling-Gang Wu in the National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland is seeking one highly motivated postdoctoral fellow. Wu lab studies membrane dynamics underlying vesicle docking, fusion, transmitter release, endocytosis and recycling in secretory neuroendocrine cells and synapses. Wu lab uses STED, PALM/STORM and MINFLUX nanoscopy at ~50–1 nm resolution to directly visualize single molecules in driving membrane dynamics, such as vesicle docking, fusion pore opening, expansion and closure, as well as endocytic flat-to-round membrane curvature transformation that forms vesicles. Combining these super-resolution imaging techniques with molecular biology, electrophysiology and electron microscopy, Wu lab aims to understand fusion and endocytosis at the level of single molecules in the nano-meter scale at a fast temporal resolution in physiological conditions and in disorders. Further details can be found at https://irp.nih.gov/pi/ling-gang-wu.

Requirements

Applicants should have a Ph.D. in cell biology, biophysics, molecular biology, neuroscience, structural biology or biology.  Desirable skills may include some of the following techniques: confocal imaging, super-resolution imaging, molecular biology, electrophysiology, electron microscopy, cryo EM, and/or structural biology experience. Salary will be commensurate with experiences. Applications should include CV, representative publications, the names of three referees, and a cover letter detailing their qualification, interest and long-term goal. Applications should be sent by email to Dr. Ling-Gang Wu at wul@ninds.nih.gov. The positions are available immediately and will remain open until filled.